The following are the major areas of research of the PFC-DSEER:
- Water and environmental research
- Energy research
- Dead Sea Phenomena
- Dead Sea circulation
- Hydrodynamics of the Dead Sea
- Evaporation from the Dead Sea
- Mass Transfer and Diffusion
- Dead Sea Analysis
- Chemical Analysis
- Biological Analysis
- Salt Precipitation
- Crystallization
- Mud (medical treatment)
- Dead Sea bed studies
- Geological studies
- Geophysical studies
- Ground water intrusion
- Research related to Dead Sea industries
- Potash
- Bromine
- pharmaceutical products and cosmetic and others